When patent, the minor duodenal papilla may be associated with recurrent pancreatitis. The minor duodenal papilla represents the remnants of the opening of the accessory pancreatic duct, which drains the dorsal pancreatic bud during foetal development. The duct is an embryological remnant, however in a small majority of people drains the pancreas. Pain from the region will be referred to the epigastric region of the abdomen due to its associated dermatomes. In 10% of people, the minor duodenal papilla is the prime duct for drainage of the pancreas, although in others it may not be present at all. When present, the sphincter is known as the sphincter of Helly, and the duct as the accessory pancreatic duct of Santorini. The minor duodenal papilla may or may not contain a functioning sphincter and patent duct. The gastroduodenal artery lies posterior. It is situated 2 cm proximal to the major duodenal papilla, and thus 5–8 cm from the opening of the pylorus. The minor duodenal papilla is contained within the second part of the duodenum. The minor duodenal papilla is the opening of the accessory pancreatic duct into the descending second section of the duodenum.
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